Back Cover: One‐pot Conversion of Cycloalkanes to Lactones (ChemCatChem 2/2015). Issue 2 (January 2015)

• Record Type: Journal Article
• Authors: Pennec, Alizé; Hollmann, Frank; Smit, Martha S.; Opperman, Diederik J.
• Is Part Of: ChemCatChem. Volume 7:Issue 2(2015:Jan.)
• Page Start: 356
• Page End: 356
• Publication Date: 2015-01
• Subjects: Catalysis -- Periodicals; 541.39505
• DOI: 10.1002/cctc.201590011
• Languages: English
• ISSNs: 1867-3880

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The cover picture shows</bold> the one‐pot conversion of cycloalkanes to lactones. In their Communication, A. Pennec et al. describe a redox‐balanced synthetic pathway consisting of a cytochrome P450 monooxygenase (CYP450) for initial oxyfunctionalization of the cycloalkane, an alcohol dehydrogenase for ketone production and a Baeyer–Villiger monooxygenase for lactone formation. Product yields were increased by uncoupling the co‐factor requirements between the multiple oxidation reduction steps through variation of the cofactor dependence of the biocatalysts and the cofactor regeneration system. The article highlighted by this cover can be found on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">p. 236 ff.</ext-link> of Issue 2, 2015.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh31tn5ntn" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>