2C-I-NBOMe, an "N-bomb" that kills with "Smiles". Toxicological and legislative aspects. (January 2015)

• Record Type: Journal Article
• Authors: Nikolaou, Panagiota; Papoutsis, Ioannis; Stefanidou, Maria; Spiliopoulou, Chara; Athanaselis, Sotiris
• Is Part Of: Drug and chemical toxicology. Volume 38:Number 1(2015:Jan.)
• Page Start: 113
• Page End: 119
• Publication Date: 2015-01
• Subjects: Toxicology -- Periodicals; Drugs -- Toxicology -- Periodicals; Toxicology, Experimental -- Periodicals; 615.9005
• DOI: 10.3109/01480545.2014.911882
• Languages: English
• ISSNs: 0148-0545

Abstract

<abstract> <title>Abstract</title> <p>Substituted phenethylamines are a class of designer drugs that have recently emerged in the drug abuse market. Such substances remain legal to use, possess, and supply until these compounds become classified as scheduled. 2C-I-NBOMe or 25I-NBOMe is the N-benzyl-derivative of the iodo-substituted dimethoxy-phenethylamine (2C-I) that appeared recently in the drug market under the street name "N-Bomb". Due to its high potency, intoxications and fatal cases related to 2C-I-NBOMe use are increased worldwide. The use and trafficking of this substituted phenethylamine is banned only in some countries. A comprehensive review was performed using PubMed and Medline databases, together with additional non-peer reviewed information sources, including books and publications of state authorities in different countries, regarding chemistry, availability, pharmacology, and toxicology of 2C-I-NBOMe. Intoxications or lethal cases, published or reported, as well as the current legislation on this newly introduced drug are also reviewed.</p> </abstract>