Atopy patch test with Aleuroglyphus ovatus antigen in patients with atopic dermatitis. (13th March 2014)

• Record Type: Journal Article
• Authors: Lorenzini, D.; Pires, M.; Aoki, V.; Takaoka, R.; Souza, R.L.; Vasconcellos, C.
• Is Part Of: Journal of the European Academy of Dermatology and Venereology. Volume 29:Number 1(2015:Jan.)
• Page Start: 38
• Page End: 41
• Publication Date: 2014-03-13
• Subjects: Dermatology -- Periodicals; Sexually transmitted diseases -- Periodicals; 616.5
• DOI: 10.1111/jdv.12429
• Languages: English
• ISSNs: 0926-9959

Abstract

<abstract abstract-type="main" id="jdv12429-abs-0001"> <title>Abstract</title> <sec id="jdv12429-sec-0001" sec-type="section"> <title>Background</title> <p>Epicutaneous test made with dust mite antigens.</p> </sec> <sec id="jdv12429-sec-0002" sec-type="section"> <title>Objective</title> <p>Evaluation of the response of the epicutaneous test with <italic>Aleuroglyphus ovatus</italic> antigen in atopic patients.</p> </sec> <sec id="jdv12429-sec-0003" sec-type="section"> <title>Methods</title> <p>We patch tested 119 individuals, 48 with atopic dermatitis, 50 with respiratory allergy and 21 healthy controls. We compare the positive response frequency to a closed patch test using <italic>Aleuroglyphus ovatus</italic> antigen in different concentrations and 48 and 96h reading times among those individuals.</p> </sec> <sec id="jdv12429-sec-0004" sec-type="section"> <title>Results</title> <p>Six patients with atopic dermatitis (12.5%) and 4 with respiratory atopy (8.0%) had positive reactions. None of the non‐atopic controls had a positive response. As the antigen concentration raised, the number of positive reactions to epicutaneous test raised as well.</p> </sec> <sec id="jdv12429-sec-0005" sec-type="section"> <title>Conclusion</title> <p>Our data suggest a positive relation between Atopy Patch Test positive responses and <italic>Aleuroglyphus ovatus</italic> antigen concentration, no matter the kind of the atopic clinical expression.</p> </sec> </abstract>