The Canadian Healthy Infant Longitudinal Development Birth Cohort Study: Biological Samples and Biobanking. Issue 1 (18th November 2014)

• Record Type: Journal Article
• Authors: Moraes, T. J.; Lefebvre, D. L.; Chooniedass, R.; Becker, A. B.; Brook, J. R.; Denburg, J.; HayGlass, K. T.; Hegele, R. G.; Kollmann, T. R.; Macri, J.; Mandhane, P. J.; Scott, J. A.; Subbarao, P.; Takaro, T. K.; Turvey, S. E.; Duncan, J. D.; Sears, M. R.; Befus, A. D.; CHILD Study Investigators
• Is Part Of: Paediatric and perinatal epidemiology. Volume 29:Issue 1(2015)
• Page Start: 84
• Page End: 92
• Publication Date: 2014-11-18
• Subjects: Pediatrics -- Periodicals; Perinatology -- Periodicals; Pediatric epidemiology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; 618.92
• DOI: 10.1111/ppe.12161
• Languages: English
• ISSNs: 0269-5022

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="ppe12161-sec-0001" sec-type="section"> <title>Background</title> <p>It is hypothesised that complex interactions between genetic and environmental factors give rise to allergy and asthma in childhood. The Canadian Healthy Infant Longitudinal Development (CHILD) study was designed to explore these factors.</p> </sec> <sec id="ppe12161-sec-0002" sec-type="section"> <title>Methods</title> <p>CHILD is a longitudinal, general population birth cohort study following infants from mid‐pregnancy to age 5 years. Over this time period, biological samples, questionnaires, clinical measures and environmental data are collected.</p> </sec> <sec id="ppe12161-sec-0003" sec-type="section"> <title>Results</title> <p>A total of 3624 families have been recruited, and many thousands of samples and questionnaires have been collected, annotated, and archived. This report outlines the rationale and methodology for collecting and storing diverse biological samples from parents and children in this study, and the mechanisms for their release for analyses.</p> </sec> <sec id="ppe12161-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The CHILD sample and data repository is a tremendous current and future resource and will provide a wealth of information not only informing studies of asthma and allergy, but also potentially in many other aspects of health relevant for Canadian infants and children.</p> </sec> </abstract>