Comparing lung ultrasound with bioimpedance spectroscopy for evaluating hydration in peritoneal dialysis patients. (January 2015)

• Record Type: Journal Article
• Authors: Paudel, Klara; Kausik, Tarun; Visser, Annemarie; Ramballi, Cheryl; Fan, Stanley L
• Is Part Of: Nephrology. Volume 20:Number 1(2015)
• Page Start: 1
• Page End: 5
• Publication Date: 2015-01
• Subjects: Nephrology -- Periodicals; Kidneys -- Diseases -- Periodicals; Nephrologists -- Periodicals; 616.61; 616.61
• DOI: 10.1111/nep.12342
• Languages: English
• ISSNs: 1320-5358

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="nep12342-sec-0001" sec-type="section"> <title>Background</title> <p>Bioimpedance spectroscopy (BIS), ultrasound lung comets (ULC) and serum biomarkers (<italic>N</italic>‐terminal pro–brain natriuretic peptide, NT‐proBNP) have all been used to assist clinicians to determine hydration status in dialysis patients.</p> </sec> <sec id="nep12342-sec-0002" sec-type="section"> <title>Methods</title> <p>We performed simultaneous BIS, ULC and NT‐proBNP measurements in 27 peritoneal dialysis patients to determine the concordance of the three methods.</p> </sec> <sec id="nep12342-sec-0003" sec-type="section"> <title>Results</title> <p>Patients with evidence of increasing lung congestion (as determined by ultrasound) were more likely to be diabetic, have systolic hypertension and have higher NT‐proBNP (<italic>r</italic> = 0.65, <italic>P</italic> < 0.0005). Although there was a trend for patients with high ULC to be overhydrated as determined by BIS, this did not reach statistical significance. Moreover, the correlation between BIS and NT‐proBNP (though statistically significant at <italic>r</italic> = 0.47, <italic>P</italic> < 0.02) appeared to be weaker.</p> </sec> <sec id="nep12342-sec-0004" sec-type="section"> <title>Conclusion</title> <p>BIS and ULC may be complementary, providing different information, whereas BIS may be more specific to hydration. ULC and NT‐proBNP may indicate left ventricular failure coexisting with overhydration.</p> </sec> </abstract>