Successfully achieving target weight loss influences subsequent maintenance of lower weight and dropout from treatment. (16th October 2014)

• Record Type: Journal Article
• Authors: Yamada, Tomohide; Hara, Kazuo; Svensson, Akiko Kishi; Shojima, Nobuhiro; Hosoe, Jun; Iwasaki, Minaka; Yamauchi, Toshimasa; Kadowaki, Takashi
• Is Part Of: Obesity. Volume 23:Number 1(2015:Jan.)
• Page Start: 183
• Page End: 191
• Publication Date: 2014-10-16
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.20874
• Languages: English
• ISSNs: 1930-7381

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="oby20874-sec-0001" sec-type="section"> <title>Objectives</title> <p>The influence of the amount and rate of weight loss on subsequently regaining weight and dropout from treatment in severely obese patients targeting 5% weight loss was investigated.</p> </sec> <sec id="oby20874-sec-0002" sec-type="section"> <title>Methods</title> <p>A total of 120 consecutive hospital patients with severe obesity (BMI: 42 ± 9 kg/m<sup>2</sup>) participated in an inpatient program targeting 5% weight loss that involved goal setting, charting weight four times daily, and diet and exercise. They were followed after discharge to assess subsequent regaining of weight and dropout.</p> </sec> <sec id="oby20874-sec-0003" sec-type="section"> <title>Results</title> <p>Mean weight loss was 4.9 ± 2.4% after a mean of 19 days in the hospital, and 43% of the patients achieved the target weight loss (>5%). Over the median 2‐year follow‐up period, greater than 5% in‐hospital weight loss was associated with a significantly lower risk of regaining weight after adjustment for various factors (>5% to ≤7% loss: hazard ratio 0.30 [0.11‐0.85] for regaining all of the lost weight and 0.32 [0.13‐0.78] for regaining half of the lost weight). No significant relation between the amount or rate of weight loss and dropout from subsequent outpatient treatment was seen.</p> </sec> <sec id="oby20874-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Successfully achieving the target weight loss in a comprehensive program predicts subsequent maintenance of lower weight without increasing the risk of dropout. Successful in‐hospital weight loss might increase the motivation of obese patients.</p> </sec> </abstract>