A Highly Selective and Sensitive Turn‐On Fluorescent Chemosensor Based on Rhodamine 6G for Iron(III)1. Issue 6 (26th November 2014)

• Record Type: Journal Article
• Authors: Hu, Zhi-Qiang; Gu, Ying-Ying; Hu, Wen-Zhou; Sun, Lei-Li; Zhu, Jiang-Hua; Jiang, Yi
• Is Part Of: ChemistryOpen. Volume 3:Issue 6(2014:Dec.)
• Page Start: 264
• Page End: 268
• Publication Date: 2014-11-26
• Subjects: Chemistry -- Periodicals; 540; 540.5
• DOI: 10.1002/open.201402065
• Languages: English
• ISSNs: 2191-1363

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Recently, more and more rhodamine derivatives have been used as fluorophores to construct sensors due to their excellent spectroscopic properties. A rhodamine‐based fluorescent and colorimetric Fe³⁺ chemosensor 3', 6'‐bis(ethylamino)‐2‐acetoxyl‐2', 7'‐dimethyl‐spiro[1<italic>H</italic>‐isoindole‐1, 9'‐[9<italic>H</italic>]xanthen]‐3(2<italic>H</italic>)‐one (<bold>RAE</bold>) was designed and synthesized. Upon the addition of Fe³⁺, the dramatic enhancement of both fluorescence and absorbance intensity, as well as the color change of the solution, could be observed. The detection limit of <bold>RAE</bold> for Fe³⁺ was around 7.98 ppb. Common coexistent metal ions showed little or no interference in the detection of Fe³⁺. Moreover, the addition of CN⁻ could quench the fluorescence of the acetonitrile solution of <bold>RAE</bold> and Fe³⁺, indicating the regeneration of the chemosensor <bold>RAE</bold>. The robust nature of the sensor was shown by the detection of Fe³⁺ even after repeated rounds of quenching. As iron is a ubiquitous metal in cells and plays vital roles in many biological processes, this chemosensor could be developed to have applications in biological studies.</p> </abstract>