Clinical use of oxygen‐enhanced T1 mapping MRI of the lung: Reproducibility and impact of closed versus loose fit oxygen delivery system. Issue 1 (12th December 2013)

• Record Type: Journal Article
• Authors: Renne, Julius; Lauermann, Peer; Hinrichs, Jan; Schönfeld, Christian; Sorrentino, Sajoscha; Gutberlet, Marcel; Jakob, Peter; Wacker, Frank; Vogel‐Claussen, Jens
• Is Part Of: Journal of magnetic resonance imaging. Volume 41:Issue 1(2015)
• Page Start: 60
• Page End: 66
• Publication Date: 2013-12-12
• Subjects: Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.24535
• Languages: English
• ISSNs: 1053-1807

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmri24535-sec-0001" sec-type="section"> <title>Purpose</title> <p>To evaluate the reproducibility of oxygen‐enhanced magnetic resonance imaging (MRI), and the influence of different gas delivery methods, in a clinical environment.</p> </sec> <sec id="jmri24535-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>Twelve healthy volunteers were examined on two visits with an inversion recovery snapshot fast low angle shot sequence on a 1.5 T system. Coronal slices were obtained breathing room air as well as 100% oxygen with a flow rate of 15 L/min. For oxygen delivery a standard nontight face mask and a full closed air‐cushion face mask were used. T<sub>1</sub> relaxation times and the oxygen transfer function (OTF) were calculated.</p> </sec> <sec id="jmri24535-sec-0003" sec-type="section"> <title>Results</title> <p>The mean T<sub>1</sub> values did not change significantly between the two visits (<italic>P</italic> > 0.05). The T<sub>1</sub> values breathing 100% oxygen obtained using the full closed mask were significantly lower (1093 ± 38 msec; <italic>P</italic> < 0.05) compared to the standard mask (1157 ± 52 msec). Accordingly, the OTF was significantly higher for the full closed mask (<italic>P</italic> < 0.05). The OTF changed significantly on the second visit using the standard mask (<italic>P</italic> < 0.05). The full closed mask showed lower interindividual variation for both the T<sub>1</sub> values (3.5% vs. 4.5%) as well as the OTF (12.4% vs. 22.0%) and no difference of the OTF on the second visit (<italic>P</italic> > 0.05).</p> </sec> <sec id="jmri24535-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Oxygen‐enhanced T<sub>1</sub> mapping MRI produces reproducible data when using a full closed face mask. <bold>J. Magn. Reson. Imaging 2015;41:60–66.</bold> © <bold>2013 Wiley Periodicals, Inc</bold>.</p> </sec> </abstract>