<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>CuO nanoparticles are found to be efficient catalysts for the reaction of N‐arylamidines (I) and (IV) and aromatic aldehydes (II) or benzyl alcohols (VI) to afford quinazolines (III) and (V), resp., in good to high yields.</p> </abstract>