Subthalamic deep brain stimulation effects on odor identification in Parkinson's disease. (6th March 2014)

• Record Type: Journal Article
• Authors: Fabbri, M.; Guedes, L. C.; Coelho, M.; Simão, D.; Abreu, D.; Rosa, M. M.; Silveira‐Moriyama, L.; Ferreira, J. J.
• Is Part Of: European journal of neurology. Volume 22:Number 1(2015:Jan.)
• Page Start: 207
• Page End: 210
• Publication Date: 2014-03-06
• Subjects: Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; 616.8
• DOI: 10.1111/ene.12396
• Languages: English
• ISSNs: 1351-5101

Abstract

<abstract abstract-type="main" id="ene12396-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ene12396-sec-0001" sec-type="section"> <title>Background and purpose</title> <p>Olfactory dysfunction is common in Parkinson's disease (PD) and it is one of the earliest non‐motor symptoms. A few studies have suggested that deep brain stimulation of the subthalamic nucleus (STN‐DBS) could improve olfactory function. Our aim was to evaluate the acute effect of bilateral STN‐DBS on a commonly used smell test in PD patients.</p> </sec> <sec id="ene12396-sec-0002" sec-type="section"> <title>Methods</title> <p>Fifteen PD patients who underwent bilateral STN‐DBS and 15 controls were recruited. Patients and controls were tested for odor identification.</p> </sec> <sec id="ene12396-sec-0003" sec-type="section"> <title>Results</title> <p>No statistical differences were documented between ON and OFF STN‐DBS acute stimulation concerning olfaction. Controls presented a better performance for olfactory identification than patients.</p> </sec> <sec id="ene12396-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Our exploratory study did not support that bilateral STN‐DBS could have an acute effect on olfactory function in PD patients.</p> </sec> </abstract>