Back Cover: Introducing an In Situ Capping Strategy in Systems Biocatalysis To Access 6‐Aminohexanoic acid (Angew. Chem. Int. Ed. 51/2014). Issue 51 (2nd December 2014)

• Record Type: Journal Article
• Authors: Sattler, Johann H.; Fuchs, Michael; Mutti, Francesco G.; Grischek, Barbara; Engel, Philip; Pfeffer, Jan; Woodley, John M.; Kroutil, Wolfgang
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 51(2014)
• Page Start: 14274
• Page End: 14274
• Publication Date: 2014-12-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201411133
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The one‐pot synthesis of a nylon‐6 monomer by a combination of two redox self‐sufficient biocatalytic modules (gray box and flask) is described by W. Kroutil et al. in their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 14153 ff.</ext-link> The cascade is shown as an electric circuit, whereby each enzyme is shown at a crossing and an in situ capping strategy prevents dead‐end inhibition by an intermediate. The proof of principle was shown by the synthesis of 6‐aminohexanoic acid starting from cyclohexanol only at the expense of NH₃ and O₂. The graphic was designed by Verena Andrea Resch<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh2qxfhd55" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>