Bloodstream infections due to Peptoniphilus spp.: report of 15 cases. (14th June 2014)

• Record Type: Journal Article
• Authors: Brown, K.; Church, D.; Lynch, T.; Gregson, D.; Raoult, D.
• Is Part Of: Clinical microbiology and infection. Volume 20:Number 11(2014:Nov.)
• Page Start: O857
• Page End: O860
• Publication Date: 2014-06-14
• Subjects: Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1111/1469-0691.12657
• Languages: English
• ISSNs: 1198-743X

Abstract

<abstract abstract-type="main" id="clm12657-abs-0001"> <title>Abstract</title> <p> <italic>Peptoniphilus</italic> spp. are Gram‐positive anaerobic cocci (GPAC) that were formerly classified in the genus <italic>Peptostreptococcus</italic>. This study describes 15 cases of <italic>Peptoniphilus</italic> spp. bloodstream infection (BSI) diagnosed from 2007 to 2011 using 16S rDNA sequencing in patients with pneumonia, pre‐term delivery, soft tissue infection or colon or bladder disease. Seven out of 15 (47%) of these cases had polymicrobial BSIs. One of the isolates was closely related to <italic>P. duerdenii</italic> (<ext-link ext-link-type="gen" xlink:href="http://www.ncbi.nlm.nih.gov/nuccore/EU526290?report=GenBank" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">EU526290</ext-link>), while the other 14 isolates were most closely related to a <italic>Peptoniphilus</italic> sp. reference strain (ATCC 29743) and <italic>P. hareii</italic> (Y07839). <italic>Peptoniphilus</italic> is a rare but important cause of BSI.</p> </abstract>