Pre-operative cellularity mapping and intra-MRI surgery: potential for improving neurosurgical biopsies. (January 2014)

• Record Type: Journal Article
• Authors: Chen, Clark C; White, Nathan S; Farid, Nikdokht; Kobalka, Peter; Hansen, Lawrence; Pearn, Matthew; Dale, Anders M
• Is Part Of: Expert review of medical devices. Volume 12:Number 1(2015)
• Page Start: 1
• Page End: 5
• Publication Date: 2014-01
• Subjects: Medical instruments and apparatus -- Periodicals; 610.28
• DOI: 10.1586/17434440.2015.975118
• Languages: English
• ISSNs: 1743-4440

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Stereotactic biopsies are frequently performed to secure definitive diagnosis for brain tumor patients. Fundamentally, there are two major difficulties in these endeavors. First, because of intra-tumoral heterogeneity inherent in many forms of brain cancer, biopsies taken from one region may yield a different diagnosis than if another area is biopsied. Second, stereotactic needle biopsies inherently rely on mathematical algorithms for targeting, without real-time visualization of the actual biopsy site. This article describes the novel MRI-based technologies that can potentially afford neurosurgeons the opportunity to address these challenges.</p> </abstract>