Methicillin‐susceptible Staphylococcus aureus clonal complex 398: high prevalence and geographical heterogeneity in bone and joint infection and nasal carriage. (6th March 2014)

• Record Type: Journal Article
• Authors: Valour, F.; Tasse, J.; Trouillet‐Assant, S.; Rasigade, J.‐P.; Lamy, B.; Chanard, E.; Verhoeven, P.; Decousser, J.‐W.; Marchandin, H.; Bès, M.; Chidiac, C.; Vandenesch, F.; Ferry, T.; Laurent, F.; the Lyon Bone and Joint Infection study group; Tassios, P.
• Is Part Of: Clinical microbiology and infection. Volume 20:Number 10(2014:Oct.)
• Page Start: O772
• Page End: O775
• Publication Date: 2014-03-06
• Subjects: Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1111/1469-0691.12567
• Languages: English
• ISSNs: 1198-743X

Abstract

<abstract abstract-type="main" id="clm12567-abs-0001"> <title>Abstract</title> <p>The prevalence of clonal complex (CC) 398 methicillin‐susceptible <italic>Staphylococcus aureus</italic> (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal‐colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most‐known staphylococcal virulence genes, MSSA CC398 BJI was associated with lower biological inflammatory syndrome and lower treatment failure rates.</p> </abstract>