Predominance of Gram‐negative bacilli among patients with catheter‐related bloodstream infections. (20th February 2014)

• Record Type: Journal Article
• Authors: Braun, E.; Hussein, K.; Geffen, Y.; Rabino, G.; Bar‐Lavie, Y.; Paul, M.; Tacconelli, E.
• Is Part Of: Clinical microbiology and infection. Volume 20:Number 10(2014:Oct.)
• Page Start: O627
• Page End: O629
• Publication Date: 2014-02-20
• Subjects: Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1111/1469-0691.12565
• Languages: English
• ISSNs: 1198-743X

Abstract

<abstract abstract-type="main" id="clm12565-abs-0001"> <title>Abstract</title> <p>We evaluated changes in the epidemiology of catheter‐related bloodstream infections (CRBSIs) between 1996 and 2012 in a tertiary care centre in Israel. The cohort included 1754 episodes of CRBSI. The incidence of CRBSIs decreased throughout the study period, whereas 30‐day mortality following bacteraemia increased. There was a linear shift toward predominance of Gram‐negative bacilli throughout the study period (p for trend&lt;0.001). In 1996, 68% (68/100) of CRBSIs were caused by Gram‐positive cocci, whereas in 2012 77.8% (28/26) were caused by Gram‐negative bacilli. The shift towards Gram‐negative CRBSIs and the associated mortality mandates that empirical treatment for CRBSIs be directed by local epidemiology.</p> </abstract>