A High Sensitivity Electrochemical Sensor Based on Fe3+‐Ion Molecularly Imprinted Film for the Detection of T‐2 Toxin. Issue 12 (28th October 2014)

• Record Type: Journal Article
• Authors: Gao, Xing; Cao, Wenying; Chen, Miaomiao; Xiong, Huayu; Zhang, Xiuhua; Wang, Shengfu
• Is Part Of: Electroanalysis. Volume 26:Issue 12(2014:Dec.)
• Page Start: 2739
• Page End: 2746
• Publication Date: 2014-10-28
• Subjects: Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201400237
• Languages: English
• ISSNs: 1040-0397

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The excellent detection sensitivity in various matrices of T‐2 toxin (T‐2), which has cytotoxic and immunosuppressive effects in DNA and RNA synthesis, is a highly desirable characteristic. A sensitive molecularly imprinted electrochemical sensor was constructed for the selective detection of T‐2. In this study, iron ions (Fe³⁺) were introduced to increase the chelation of the metal ions and templates for preparing molecularly imprinted polymers (MIPs). With the increased chelation of the metal ions and templates, the selectivity and sensitivity of the MIPs were effectively improved. The imprinted sensor was successfully employed to detect T‐2 in cereals and human serum samples.</p> </abstract>