Antibacterial Drug Release Electrochemically Stimulated by the Presence of Bacterial Cells – Theranostic Approach. Issue 12 (21st October 2014)

• Record Type: Journal Article
• Authors: Gamella, Maria; Guz, Nataliia; Mailloux, Shay; Pingarrón, José M.; Katz, Evgeny
• Is Part Of: Electroanalysis. Volume 26:Issue 12(2014:Dec.)
• Page Start: 2552
• Page End: 2557
• Publication Date: 2014-10-21
• Subjects: Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201400473
• Languages: English
• ISSNs: 1040-0397

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A modified electrode with bioaffinity to <italic>E. coli</italic> bacterial cells was used to detect bacteria presence on its surface and to produce an electrical signal triggering antibacterial drug release from another coupled electrode. The <italic>Sense‐and‐Treat</italic> system was realized in two different versions and suggested as the first step to future theranostic applications where bacteria presence results in automatic antibacterial treatment.</p> </abstract>