Assisted Tandem Palladium(II)/Palladium(0)‐Catalyzed C‐ and N‐Arylations of Quinoxalin‐2(1 H)‐ones in Water. Issue 18 (6th November 2014)

• Record Type: Journal Article
• Authors: Carrër, Amandine; Brion, Jean‐Daniel; Alami, Mouad; Messaoudi, Samir
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 18(2014)
• Page Start: 3821
• Page End: 3830
• Publication Date: 2014-11-06
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201400662
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A straightforward assisted tandem palladium(II)‐ and palladium(0)‐catalyzed direct C‐3 and <italic>N</italic>‐4 arylation of quinoxalin‐2(1 <italic>H</italic>)‐ones with boronic acids and aryl halides in water as safe and cheap solvent is reported. This environmentally friendly catalytic protocol is compatible with a wide range of functional groups and allows construction of various biologically important quinoxalin‐2(1 <italic>H</italic>)‐one backbones.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh2qst25xp" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>