Effectiveness of zonisamide in a patient with Parkinson's disease and various levodopa‐induced psychotic symptoms. Issue 6 (9th October 2014)

• Record Type: Journal Article
• Authors: Yabe, Ichiro; Ohta, Midori; Egashira, Toshiaki; Sato, Kazunori; Kano, Takahiro; Hirotani, Makoto; Kunieda, Yasuyuki; Sasaki, Hidenao
• Is Part Of: Neurology and clinical neuroscience. Volume 2:Issue 6(2014:Nov.)
• Page Start: 201
• Page End: 203
• Publication Date: 2014-10-09
• Subjects: Neurology -- Periodicals; Neurosciences -- Periodicals; 616.8
• DOI: 10.1111/ncn3.126
• Languages: English
• ISSNs: 2049-4173

Abstract

<abstract abstract-type="main" id="ncn3126-abs-0001"> <title>Abstract</title> <p>Levodopa and dopamine agonists are useful as Parkinson's disease medications. However, they often induce persistent psychotic symptoms and motor complications, which make Parkinson's disease treatment difficult. This is a case report of a patient with advanced Parkinson's disease accompanied by exacerbation of motor symptoms and psychotic symptoms derived from prolonged use of conventional anti‐Parkinson's disease drugs, and in whom adjunctive therapy with a new anti‐Parkinson's disease drug, zonisamide, was shown to improve motor symptoms with no exacerbation of psychotic symptoms.</p> </abstract>