Depression and psychosocial correlates of liver transplant candidates: A systematic review. (8th August 2014)

• Record Type: Journal Article
• Authors: Mohamed, Salina; Sabki, Zuraida Ahmad; Zainal, Nor Zuraida
• Is Part Of: Asia-Pacific psychiatry. Volume 6:Number 4(2014:Dec.)
• Page Start: 447
• Page End: 453
• Publication Date: 2014-08-08
• Subjects: Psychiatry -- Pacific Area -- Periodicals; 616.890095
• DOI: 10.1111/appy.12145
• Languages: English
• ISSNs: 1758-5864

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="appy12145-sec-0001" sec-type="section"> <title>Introduction</title> <p>Liver transplant candidates are vulnerable to develop depression. This paper aims to ascertain the prevalence of depression in liver transplant candidates and its psychosocial factors in a systematic review.</p> </sec> <sec id="appy12145-sec-0002" sec-type="section"> <title>Methods</title> <p>An extensive review via electronic databases (PubMed, EMBASE, CINAHL) and hand search were carried out to retrieve published articles up to December 15, 2013, using (Incidence OR Prevalence) AND Depress* AND liver transplant as the keywords. Information on the study design, patient characteristics, prevalence of depression, and its associated risk factors were extracted from included studies.</p> </sec> <sec id="appy12145-sec-0003" sec-type="section"> <title>Results</title> <p>There were 22 studies included in this review with a total of 3055 patients. The prevalence of depression in the liver transplant candidates ranges between 2% and 80%. Studies that used diagnostic tools found a narrower range of prevalence (4.5–43%) as compared to the self‐administered questionnaires (2–80%). Studies that used Beck Depression Inventory reported a higher prevalence than those studies which used Hospital Anxiety and Depression Scale (median = 28%, range = 2–80% versus median 17%, range 6.1–25.8%). A number of socio‐demographic factors, illness‐related and psychosocial factors were found to be associated with depression.</p> </sec> <sec id="appy12145-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Prevalence of depression in liver transplant candidates is high, and early detection will improve survival and quality of life.</p> </sec> </abstract>