Patterns of weight change in black Americans: Pooled analysis from three behavioral weight loss trials. (24th September 2014)

• Record Type: Journal Article
• Authors: Morales, Knashawn H.; Kumanyika, Shiriki K.; Fassbender, Jennifer E.; Good, Jerene; Localio, A. Russell; Wadden, Thomas A.
• Is Part Of: Obesity. Volume 22:Number 12(2014:Dec.)
• Page Start: 2632
• Page End: 2640
• Publication Date: 2014-09-24
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.20904
• Languages: English
• ISSNs: 1930-7381

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="oby20904-sec-0001" sec-type="section"> <title>Objective</title> <p>Differentiating trajectories of weight change and identifying associated baseline predictors can provide insights for improving behavioral obesity treatment outcomes.</p> </sec> <sec id="oby20904-sec-0002" sec-type="section"> <title>Methods</title> <p>Secondary, observational analyses using growth mixture models were conducted in pooled data for 604 black American, primarily female adults in three completed clinical trials. Covariates of identified patterns were evaluated.</p> </sec> <sec id="oby20904-sec-0003" sec-type="section"> <title>Results</title> <p>The best fitting model identified three patterns over 2 years: 1) mean weight loss of approximately 2 kg (<italic>n</italic> = 519); 2) mean weight loss of approximately 3 kg at 1 year, followed by ∼4 kg regain (<italic>n</italic> = 61); and 3) mean weight loss of ∼20 kg at 1 year followed by ∼4 kg regain (<italic>n</italic> = 24, with 23 from one study). In final multivariate analyses, higher BMI predicted having pattern 2 (OR [95% CI]) 1.10 [1.03, 1.17]) or 3 (OR [95% CI] 1.42 [1.25, 1.63]), and higher dietary fat score was predictive of a lower odds of having patterns 2 (OR [95% CI] 0.37[0.15, 0.94]) or 3 (OR [95% CI] 0.23 [0.07, 0.79]).</p> </sec> <sec id="oby20904-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Findings were consistent with moderate, clinically non‐significant weight loss as the predominant pattern across all studies. Results underscore the need to develop novel and more carefully targeted and tailored approaches to facilitating weight loss in black American adults.</p> </sec> </abstract>