Depression, stress, and weight loss in individuals with metabolic syndrome in SHINE, a DPP translation study. (24th September 2014)

• Record Type: Journal Article
• Authors: Trief, Paula M.; Cibula, Donald; Delahanty, Linda M.; Weinstock, Ruth S.
• Is Part Of: Obesity. Volume 22:Number 12(2014:Dec.)
• Page Start: 2532
• Page End: 2538
• Publication Date: 2014-09-24
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.20916
• Languages: English
• ISSNs: 1930-7381

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="oby20916-sec-0001" sec-type="section"> <title>Objective</title> <p>To examine the relationships between elevated depression symptoms (EDS) or stress and weight loss in SHINE, a telephonic, primary‐care based, translation of the Diabetes Prevention Program.</p> </sec> <sec id="oby20916-sec-0002" sec-type="section"> <title>Methods</title> <p> <italic>N</italic> = 257 adults with metabolic syndrome were randomized to individual (IC) or group (CC) phone participation. Weight, depression, anti‐depressant use (ADMs), and stress (baseline, 6 months, 1 and 2 years) were assessed. Univariate analyses used linear and logistic regression, <italic>t</italic> tests for continuous variables and exact tests for categorical variables. Stratified analyses assessed modifiers of effects of depression/stress on weight loss.</p> </sec> <sec id="oby20916-sec-0003" sec-type="section"> <title>Results</title> <p>Approximately 35% reported EDS, with no change over time. Approximately 28% of all participants used ADMs. Participants with EDS had lower mean % weight loss and a smaller % who achieved ≥5% weight loss. Participants with EDS were less likely to be "completers" (40.1% vs. 61.5%, <italic>P</italic> = 0.002), coached (48.0% vs. 60.7%, <italic>P</italic> = 0.049), or log diet/activity (19.4% vs. 42.7%, <italic>P</italic> < 0.001), behaviors related to weight loss. Results were similar for high stress. ADM use had no independent effect on weight loss.</p> </sec> <sec id="oby20916-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Individuals with metabolic syndrome and EDS and/or high stress were less likely to lose significant weight. Pre‐intervention depression and stress screening to intervene may improve weight loss.</p> </sec> </abstract>