Whole‐body MRI‐based fat quantification: A comparison to air displacement plethysmography. Issue 6 (22nd January 2014)

• Record Type: Journal Article
• Authors: Ludwig, Ute A.; Klausmann, Florian; Baumann, Sandra; Honal, Matthias; Hövener, Jan‐Bernd; König, Daniel; Deibert, Peter; Büchert, Martin
• Is Part Of: Journal of magnetic resonance imaging. Volume 40:Issue 6(2014)
• Page Start: 1437
• Page End: 1444
• Publication Date: 2014-01-22
• Subjects: Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.24509
• Languages: English
• ISSNs: 1053-1807

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmri24509-sec-0001" sec-type="section"> <title>Purpose</title> <p>To demonstrate the feasibility of an algorithm for MRI whole‐body quantification of internal and subcutaneous fat and quantitative comparison of total adipose tissue to air displacement plethysmography (ADP).</p> </sec> <sec id="jmri24509-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>For comparison with ADP, whole‐body MR data of 11 volunteers were obtained using a continuously moving table Dixon sequence. Resulting fat images were corrected for B1 related intensity inhomogeneities before fat segmentation.</p> </sec> <sec id="jmri24509-sec-0003" sec-type="section"> <title>Results</title> <p>The performed MR measurements of the whole body provided a direct comparison to ADP measurements. The segmentation of subcutaneous and internal fat in the abdomen worked reliably with an accuracy of 98%. Depending on the underlying model for fat quantification, the resultant MR fat masses represent an upper and a lower limit for the true fat masses. In comparison to ADP, the results were in good agreement with ρ ≥0.97, <italic>P</italic> < 0.0001.</p> </sec> <sec id="jmri24509-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Whole‐body fat quantities derived noninvasively by using a continuously moving table Dixon acquisition were directly compared with ADP. The accuracy of the method and the high reproducibility of results indicate its potential for clinical applications. <bold>J. Magn. Reson. Imaging 2014;40:1437–1444</bold>. © <bold>2014 Wiley Periodicals, Inc</bold>.</p> </sec> </abstract>