The distribution of intraocular pressure and associated systemic factors in a Korean population: The Korea National Health and Nutrition Examination Survey. (22nd January 2014)

• Record Type: Journal Article
• Authors: Kim, Mi Jeung; Park, Ki Ho; Kim, Chan Yun; Jeoung, Jin Wook; Kim, Seok Hwan
• Is Part Of: Acta ophthalmologica. Volume 92:Number 7(2014)
• Page Start: e507
• Page End: e513
• Publication Date: 2014-01-22
• Subjects: Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.12327
• Languages: English
• ISSNs: 1755-375X

Abstract

<abstract abstract-type="main" id="aos12327-abs-0001"> <title>Abstract</title> <sec id="aos12327-sec-0001" sec-type="section"> <title>Purpose</title> <p>To investigate the distribution of intraocular pressure (IOP) and its associated factors in a large Korean population based on the data from the nationwide cross‐sectional survey.</p> </sec> <sec id="aos12327-sec-0002" sec-type="section"> <title>Methods</title> <p>We obtained 2009–2010 data from the Korea National Health and Nutrition Examination Survey (KNHANES) (<italic>n </italic>=<italic> </italic>17 901). After excluding individuals under 19 years of age, a total of 13 431 subjects were enrolled. All participants completed a comprehensive questionnaire and underwent an ocular examination including measurement of IOP by Goldmann applanation tonometry, as well as a systemic evaluation including blood pressure measurements, anthropometry and blood tests.</p> </sec> <sec id="aos12327-sec-0003" sec-type="section"> <title>Results</title> <p>The mean IOP in the right eye was 13.99 ± 2.75 mmHg, and in the left eye, 13.99 ± 2.75 mmHg, representing no significant bilateral difference. There was, however, a significant difference between males (14.19 ± 2.78 mmHg) and females (13.79 ± 2.70 mmHg) (p < 0.001). Multiple regression analysis revealed that higher IOP was significantly correlated with male sex, higher myopic refractive error, higher body mass index, higher systolic blood pressure, higher fasting plasma glucose and higher total cholesterol (all p < 0.05). On the other hand, age, histories of smoking or migraine or cold hands/feet were not significantly correlated with IOP (all p > 0.05).</p> </sec> <sec id="aos12327-sec-0004" sec-type="section"> <title>Conclusions</title> <p>In the general Korean population, IOP increases with male sex and increasing myopia. Further, IOP is significantly correlated with systemic factors relating to cardiovascular disease and metabolic syndrome.</p> </sec> </abstract>