Decontamination of Nosocomial Bacteria Including Clostridium difficile Spores on Dry Inanimate Surface by Cold Atmospheric Plasma. Issue 10 (8th August 2014)

• Record Type: Journal Article
• Authors: Klämpfl, Tobias G.; Shimizu, Tetsuji; Koch, Sylvia; Balden, Martin; Gemein, Stefanie; Li, Yang‐Fang; Mitra, Anindita; Zimmermann, Julia L.; Gebel, Jürgen; Morfill, Gregor E.; Schmidt, Hans‐Ulrich
• Is Part Of: Plasma processes and polymers. Volume 11:Issue 10(2014:Oct.)
• Page Start: 974
• Page End: 984
• Publication Date: 2014-08-08
• Subjects: Plasma polymerization -- Periodicals; Plasma-enhanced chemical vapor deposition -- Periodicals; Plasma chemistry -- Periodicals
• DOI: 10.1002/ppap.201400080
• Languages: English
• ISSNs: 1612-8850

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ppap201400080-sec-0001" sec-type="section"> <p>Microbial control is important to prevent nosocomial infections. Cold atmospheric plasma (CAP) is studied as an alternative disinfectant for dry surfaces. Bacterial endospores including <italic>Clostridium difficile</italic> and vegetative bacteria including <italic>Enterococcus faecium</italic> are treated on carriers, considering European testing standards. CAP reduces the spore load (10⁶ cfu) by at least 3 log₁₀ as required, independent from the bioburden (≤10 min treatments). Only a 2 log₁₀ reduction is achieved with vegetative bacteria due to multilayer formation resulting from a higher required load (10⁸ cfu). However, densities &lt;10⁻⁷ cfu cm⁻² enable disinfection by CAP. Elemental mapping identified other influencing burden. Overall, this study demonstrates possibilities and limitations of CAP treatment for disinfecting purposes.<inline-graphic xlink:href="ark:/27927/pgh2ckmxf8f" content-type="ppap201400080-gra-0001" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </sec> </abstract>