Primary non‐metastatic Ewing sarcoma of the jaw in children: Results of surgical resection and primary reconstruction. Issue 6 (25th June 2014)

• Record Type: Journal Article
• Authors: Qureshi, Sajid S.; Kembhavi, Seema; Bhagat, Monica; Laskar, Siddharth; Chinnaswamy, Girish; Vora, Tushar; Prasad, Maya; Ramadwar, Mukta; Desai, Saral; Khanna, Nehal; Kurkure, Purna; Shah, Sneha; Shankdhar, Vinay; Yadav, Prabha
• Is Part Of: Journal of surgical oncology. Volume 110:Issue 6(2014:Nov. 01)
• Page Start: 689
• Page End: 695
• Publication Date: 2014-06-25
• Subjects: Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.23698
• Languages: English
• ISSNs: 0022-4790

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <sec id="jso23698-sec-0001" sec-type="section"> <title>Background and Objective</title> <p>The rarity of Ewing sarcoma (ES) of the jaw coupled with the technical challenge of resection and associated functional and cosmetic impairment has resulted in deficient data on surgical management of these tumors. The purpose of this study is to describe the results of surgical excision and reconstruction of primary non‐metastatic ES of the mandible and maxilla in children.</p> </sec> <sec id="jso23698-sec-0002" sec-type="section"> <title>Methods</title> <p>Consecutive patients (mandible = 6, maxilla = 5) treated with surgery from August 2005 to January 2013 were selected. All patients received induction chemotherapy and were selected for surgical resection based on the presence of specific criteria for operability.</p> </sec> <sec id="jso23698-sec-0003" sec-type="section"> <title>Results</title> <p>The median age was 11.5 years (range 5–16 years). Free fibular osteocutaneous flap was commonly used for reconstruction. There were no complications related to microvascular anastomosis or flap loss. Five patients had 100% tumor necrosis and did not receive radiotherapy. Teeth alignment, chewing, swallowing, and speech were normal in all and donor site morbidity occurred in one. The 5‐year overall, event‐free survival, and local control are 87.5%, 72.9%, and 90%, respectively.</p> </sec> <sec id="jso23698-sec-0004" sec-type="section"> <title>Conclusion</title> <p>In eligible patients, surgery with contemporary reconstruction results in optimal oncological and functional outcome. Surgery also has the added advantage of identifying patients who may not need radiotherapy. <italic>J. Surg. Oncol. 2014 110:689–695</italic>. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>