A new [2H]‐labelled α‐trichloroimidate glucuronic ester for the synthesis of deuterated drug conjugates. (22nd October 2014) - Heinkele, Georg
Abstract A new reaction pathway for the synthesis of a [2H]‐labelled trichloroacetimidate precursor for the preparation of glucuronides is described. Therewith, stable isotope‐labelled drug glucuronides become accessible on a preparative scale, which can further be used as internal standards for quantitative analysis.