An Expedient Synthesis of a New Calix Frame by Lewis Acid Catalyzed Cyclocondensations of Ketones with Different Heterocyclic Ring Systems. (25th March 2014)

• Record Type: Journal Article
• Authors: Nayak, Anupam; Banerji, Julie
• Is Part Of: Journal of heterocyclic chemistry. Volume 51:Number 5(2014)
• Page Start: 1380
• Page End: 1384
• Publication Date: 2014-03-25
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.1780
• Languages: English
• ISSNs: 0022-152X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>A facile and highly efficient protocol has been developed for the synthesis of calix[4]pyrroles and tetraoxaquaterenes, in moderate to high yields by reaction of dialkyl or cycloalkyl ketones with pyrrole and furan catalyzed by tin (IV) chloride. Particularly, in the case of furan, instead of tedious column chromatography, simple filtration techniques were employed for purification of the compounds thereby yielding better results and leading to multigram scale synthesis. We also report the first synthesis of the novel tetracyclopentyl tetraoxaquaterene.</p> </abstract>