Clinical significance of intraparotid lymph node metastasis in primary parotid cancer. Issue 11 (18th December 2013)

• Record Type: Journal Article
• Authors: Lim, Chwee Ming; Gilbert, Mark R.; Johnson, Jonas T.; Kim, Seungwon
• Is Part Of: Head & neck. Volume 36:Issue 11(2014:Nov.)
• Page Start: 1634
• Page End: 1637
• Publication Date: 2013-12-18
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23507
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="hed23507-sec-0001" sec-type="section"> <title>Background</title> <p>The clinical utility of intraparotid lymph node metastasis in primary parotid cancer is unknown, and this study was undertaken to address this gap in knowledge.</p> </sec> <sec id="hed23507-sec-0002" sec-type="section"> <title>Methods</title> <p>A medical chart review was performed on 86 patients who underwent parotidectomy with neck dissection (39 cN+ and 47 cN0). The disease‐specific mortality and locoregional recurrence (LRR) were correlated with intraparotid lymph node metastasis status.</p> </sec> <sec id="hed23507-sec-0003" sec-type="section"> <title>Results</title> <p>Using intraparotid lymph node metastasis status to predict cervical nodal metastasis resulted in a sensitivity and specificity of 70% and 90.6%, respectively (positive predictive value [PPV] of 87.3%). Patients with positive intraparotid lymph node metastasis had a worse 3‐year disease‐specific mortality compared with patients with negative intraparotid lymph node metastasis (<italic>p</italic> = .0037). Patients with cN0 neck but positive intraparotid lymph node metastasis were more likely to develop locoregional recurrence than patients without intraparotid lymph node metastasis (<italic>p</italic> = .08).</p> </sec> <sec id="hed23507-sec-0004" sec-type="section"> <title>Conclusion</title> <p>In patients with cN0 neck but positive intraparotid lymph node metastasis, intraparotid lymph node metastasis presence was strongly associated with a worse disease‐specific survival and placed them at a higher risk of locoregional recurrence. © 2013 Wiley Periodicals, Inc. <italic>Head Neck</italic> 36: 1634–1637, 2014</p> </sec> </abstract>