Helicobacter pylori detected in pharyngeal and laryngeal pathologies in patients with proven gastric colonization. Issue 11 (12th December 2013)

• Record Type: Journal Article
• Authors: Fellmann, Jonas; Weisert, Jan U.; Soltermann, Alex; Morand, Grégoire; Morra, Laura; Moch, Holger; Huber, Gerhard F.; Probst, Rudolf
• Is Part Of: Head & neck. Volume 36:Issue 11(2014:Nov.)
• Page Start: 1562
• Page End: 1566
• Publication Date: 2013-12-12
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23492
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="hed23492-sec-0001" sec-type="section"> <title>Background</title> <p>Helicobacter pylori is known to cause gastric cancer. Presence and carcinogenicity in the upper aerodigestive system is doubtful. This study examined the prevalence of Helicobacter pylori and related factors in biopsies from the upper aerodigestive tract (UADT) in patients with gastric colonization by Helicobacter pylori.</p> </sec> <sec id="hed23492-sec-0002" sec-type="section"> <title>Methods</title> <p>In a case series study, 26 patients with histopathologically confirmed gastric colonization were identified. A polymerase chain reaction (PCR) was performed on matched formalin‐fixed and paraffin‐embedded tissues of the stomach and the oral cavity, pharynx, or larynx.</p> </sec> <sec id="hed23492-sec-0003" sec-type="section"> <title>Results</title> <p>Helicobacter pylori was found in 38% of the samples from the oral cavity, pharynx, and larynx. An association with malignancies in these regions or possible risk factors, such as age, smoking, or alcohol, was not found.</p> </sec> <sec id="hed23492-sec-0004" sec-type="section"> <title>Conclusion</title> <p>The upper aerodigestive system seems to be an additional reservoir in a significant percentage of patients presenting with Helicobacter pylori gastritis. © 2013 Wiley Periodicals, Inc. <italic>Head Neck</italic> 36: 1562–1566, 2014</p> </sec> </abstract>