Metal–Organic Framework‐Derived Copper Nanoparticle@Carbon Nanocomposites as Peroxidase Mimics for Colorimetric Sensing of Ascorbic Acid. Issue 49 (21st October 2014)

• Record Type: Journal Article
• Authors: Tan, Hongliang; Ma, Chanjiao; Gao, Li; Li, Qian; Song, Yonghai; Xu, Fugang; Wang, Tao; Wang, Li
• Is Part Of: Chemistry. Volume 20:Issue 49(2014)
• Page Start: 16377
• Page End: 16383
• Publication Date: 2014-10-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201404960
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Metal–organic frameworks (MOFs) have emerged as very fascinating functional materials due to their diversity nature. A nanocomposite consisting of copper nanoparticles dispersed within a carbon matrix (Cu NPs@C) is prepared through a one‐pot thermolysis of copper‐based metal–organic framework precursors. Cu NPs@C can catalyze the oxidation of 3, 3′, 5, 5′‐tetramethylbenzidine (TMB) to form a colored product in the presence of H₂O₂. As a peroxidase mimic, Cu NPs@C not only has the advantages of low cost, high stability, and easy preparation, but also follows Michaelis–Menten behaviors and shows strong affinity to H₂O₂. As the Cu NPs' surfaces are free from stabilizing agent, Cu NPs@C exhibited a higher affinity to H₂O₂ than horseradish peroxidase. On the basis of the inhibitory effect of ascorbic acid (AA) on oxidation of TMB, this system serves as a colorimetric method for the detection of AA, suggesting that the present work would expand the potential applications of MOF‐derived nanocomposites in biomedical fields.</p> </abstract>