C(sp3)18F Bond Formation by Transition‐Metal‐Based [18F]Fluorination. Issue 43 (22nd September 2014)

• Record Type: Journal Article
• Authors: Liang, Steven H.; Vasdev, Neil
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 43(2014)
• Page Start: 11416
• Page End: 11418
• Publication Date: 2014-09-22
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201407065
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Without a trace?</bold> Recent advances in aliphatic radiofluorinations enabled by transition metals, specifically cobalt/salen and manganese/salen complexes, have been unveiled. These new approaches operate in a unique way which obviates the need for highly activated substrates for radiolabeling and offers a new synthetic strategy to prepare ¹⁸F‐labeled radiotracers.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh2cgjtfrk" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>