NIH Toolbox Cognition Battery (CB): Validation of Executive Function Measures in Adults. (24th June 2014)

• Record Type: Journal Article
• Authors: Zelazo, Philip David; Anderson, Jacob E.; Richler, Jennifer; Wallner-Allen, Kathleen; Beaumont, Jennifer L.; Conway, Kevin P.; Gershon, Richard; Weintraub, Sandra
• Is Part Of: Journal of the International Neuropsychological Society. Volume 20:Number 6(2014:Jun.)
• Page Start: 620
• Page End: 629
• Publication Date: 2014-06-24
• Subjects: Neuropsychology -- Periodicals; 616.8
• DOI: 10.1017/S1355617714000472
• Languages: English
• ISSNs: 1355-6177

Abstract

<abstract abstract-type="normal"> <title>Abstract</title> <p>This study describes psychometric properties of the NIH Toolbox Cognition Battery (NIHTB-CB) executive function measures in an adult sample. The NIHTB-CB was designed for use in epidemiologic studies and clinical trials for ages 3 to 85. A total of 268 self-described healthy adults were recruited at four university-based sites, using stratified sampling guidelines to target demographic variability for age (20–85 years), gender, education and ethnicity. The NIHTB-CB contains two computer-based instruments assessing executive function: the Dimensional Change Card Sort (a measure of cognitive flexibility) and a flanker task (a measure of inhibitory control and selective attention). Participants completed the NIHTB-CB, corresponding gold standard convergent and discriminant measures, and sociodemographic questionnaires. A subset of participants (<italic>N</italic>=89) was retested 7 to 21 days later. Results reveal excellent sensitivity to age-related changes during adulthood, excellent test–retest reliability, and adequate to good convergent and discriminant validity. The NIH Toolbox EF measures can be used effectively in epidemiologic and clinical studies. (<italic>JINS</italic>, 2014, <italic>20</italic>, 1–10)</p> </abstract>