Sympathetic Ophthalmia in Pediatric Age Group: Clinical Features and Challenges in Management in a Tertiary Center in Southern India. (October 2014)

• Record Type: Journal Article
• Authors: Kumar, Kshitiz; Mathai, Annie; Murthy, Somasheila I.; Jalali, Subhadra; Sangwan, Virender; Reddy Pappuru, Rajeev; Pathangay, Avinash
• Is Part Of: Ocular immunology and inflammation. Volume 22:Number 5(2014)
• Page Start: 367
• Page End: 372
• Publication Date: 2014-10
• Subjects: Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.3109/09273948.2013.841958
• Languages: English
• ISSNs: 0927-3948

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To study the clinical features and visual outcome of sympathetic ophthalmia in pediatric patients attending a tertiary care center.</p> <p> <italic>Methods</italic>: Retrospective review of patients ≤16 years with sympathetic ophthalmia seen during the period 2001–2011.</p> <p> <italic>Results</italic>: During this period, 2511 pediatric patients with open globe injuries and 14 patients with sympathetic ophthalmia were seen. Six patients developed sympathetic ophthalmia during follow-up here. The incidence rate of sympathetic ophthalmia is 0.24% (6/2511, 95% CI:0.05–0.43%). The commonest presenting signs were anterior uveitis and exudative detachment. All patients were treated with systemic steroids, while 7 patients received additional immunosuppressive therapy. Eight patients had a follow-up of more than 6 months. Mean presenting best-corrected visual acuity (1.25 ± 1.03 logMAR) in the sympathizing eye improved significant following treatment (0.42 ± 0.80 logMAR, <italic>p</italic> = 0.003).</p> <p> <italic>Conclusions</italic>: The incidence of sympathetic ophthalmia was 0.24%. Appropriate immunosuppression can lead to favorable visual outcomes in the sympathizing eye.</p> </abstract>