Prevalence of Toxoplasma gondii and Toxocara canis among Patients with Uveitis. (October 2014)

• Record Type: Journal Article
• Authors: Lim, Su Jin; Lee, Sang Eun; Kim, Sun Hyun; Hong, Sung-Hee; You, Yong Sung; Kwon, Oh Woong; Kim, Hyeun Seung
• Is Part Of: Ocular immunology and inflammation. Volume 22:Number 5(2014)
• Page Start: 360
• Page End: 366
• Publication Date: 2014-10
• Subjects: Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.3109/09273948.2013.841491
• Languages: English
• ISSNs: 0927-3948

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To investigate the prevalence of <italic>Toxoplasma gondii</italic> and <italic>Toxocara canis</italic> in patients with uveitis.</p> <p> <italic>Method</italic>: Patients with uveitis were examined. Serum antibodies to <italic>T. gondii</italic> and <italic>T. canis</italic> were tested by using enzyme-linked immunosorbent assay (ELISA). Polymerase chain reaction (PCR) was done using blood and aqueous humor (AH).</p> <p> <italic>Results</italic>: 98 patients were enrolled. Mean age was 43.5 ± 13.2 years. Six patients were seropositive for <italic>T. gondii</italic> with the following pattern—anterior uveitis: 1; posterior uveitis with retinitis: 2; pan uveitis: 2. One patient had a positive result of PCR for <italic>T.gondii</italic> in AH, who showed pan uveitis. 23 patients were positive to serum IgG for T. canis with the following clinical manifestation—granuloma: 6; pigmented scar: 3; virtrits: 6—but none were PCR positive.</p> <p> <italic>Conclusion</italic>: <italic>T.gondii</italic> and <italic>T.canis</italic> are still one of the important causes of uveitis. Ocular toxocariasis is not an uncommon cause of uveitis even in adult.</p> </abstract>