Closure of the uterine incision with one or two layers after caesarean section: a randomized controlled study in sheep*. (April 2014)

• Record Type: Journal Article
• Authors: Lapointe-Milot, Korine; Rizcallah, Edmond; Takser, Larissa; Abdelouahab, Nadia; Duvareille, Charles; Pasquier, Jean-Charles
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 27:Number 7(2014:Jul.)
• Page Start: 671
• Page End: 676
• Publication Date: 2014-04
• Subjects: Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.3109/14767058.2013.834323
• Languages: English
• ISSNs: 1476-7058

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objective</italic>: To compare the quality of the uterine scar with one or two layer closure after caesarean section by studying biomechanical and pathological properties of the scar.</p> <p> <italic>Methods</italic>: A randomized controlled trial performed on eight term pregnant ewes assigned into two groups during caesarean according to type of uterine closure: single-layer or double-layer. Hysterectomy was performed 8 months after caesarean delivery. Tensile strength of all scars and of unscarred myometrium was measured. Pathological properties of the scars were analyzed histologically.</p> <p> <italic>Results</italic>: The force required to reach the yield point was similar between scarred and unscarred myometrium (<italic>p</italic> = 0.96), and between the scars in single-layer and double-layer closure groups (<italic>p</italic> = 0.65). There was a significant increase in fibrosis width on the superficial part of the uterus in the double-layer closure group compared to the single-layer group (<italic>p</italic> = 0.02).</p> <p> <italic>Conclusions</italic>: Double-layer uterine closure modified wound healing without significant change in biomechanical properties.</p> </abstract>