Bilateral Optic Disc Swelling Following Anastrozole Therapy. (October 2014)

• Record Type: Journal Article
• Authors: Coppes, Oscar Jim Michael; Lukas, Rimas V.; Fleming, Gini F.; Nichols, Jeffrey; Tenney, Meaghan; Bernard, Jacqueline
• Is Part Of: Neuro-ophthalmology. Volume 38:Number 5(2014:Oct.)
• Page Start: 268
• Page End: 271
• Publication Date: 2014-10
• Subjects: Neuroophthalmology -- Periodicals; 617.7
• DOI: 10.3109/01658107.2014.924968
• Languages: English
• ISSNs: 0165-8107

Abstract

<abstract> <title>Abstract</title> <p>A 56-year-old female with early-stage breast cancer, stage IA grade 1 endometrial cancer, and stage IC grade 1 ovarian cancer developed sudden-onset visual changes and right inferior visual field defect following anastrozole therapy. Examination revealed severe bilateral optic disc swelling and impaired visual acuity. Laboratory work-up was otherwise unremarkable. Anastrozole was discontinued and over the next month, patient had near-complete resolution of swelling in the right eye and improvement in the left eye. This is the only reported case of optic disc swelling following anastrozole therapy.</p> </abstract>