Omalizumab therapy for allergic bronchopulmonary aspergillosis in children with cystic fibrosis: A synthesis of published evidence. Issue 5 (25th October 2013) - Tanou, Kalliopi
Summary Allergic bronchopulmonary aspergillosis (ABPA) complicating cystic fibrosis (CF) is treated with corticosteroids. Since elevated IgE is a cardinal abnormality, anti‐IgE has been used sporadically as adjuvant treatment. In eight case reports, 13 children with CF and ABPA received anti‐IgE resulting in improved FEV1, fewer respiratory symptoms and decreased corticosteroid use. Pediatr Pulmonol. 2014; 49:503–507. © 2013 Wiley Periodicals, Inc.