Medical countermeasures after a radiological event: An update from the CATO project. (November 2014)

• Record Type: Journal Article
• Authors: Leiterer, Alexandra; Bardot, Isabelle; Ménétrier, Florence; Bardot, Sébastien; Grémy, Olivier; Bérard, Philippe; Pech, Annick; Favaro, Pascal
• Is Part Of: International journal of radiation biology. Volume 90:Number 11(2014:Nov.)
• Page Start: 1043
• Page End: 1047
• Publication Date: 2014-11
• Subjects: Radiation -- Physiological effect -- Periodicals; Radiobiology -- Periodicals; 571.45
• DOI: 10.3109/09553002.2014.922715
• Languages: English
• ISSNs: 0955-3002

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: As part of the European project 'CBRN crisis management: Architecture, Technologies and Operational Procedures' (CATO), an open Toolbox is in development that will address the needs of all stakeholders from first responders to decision makers. A database on chemical, biological, radiological and nuclear (CBRN) threats, including information on medical countermeasures, will be integrated in this Toolbox.</p> <p> <italic>Results and conclusions:</italic> After a radiological accident, review of national and international recommendations for the major countermeasures (stable iodine, Prussian Blue, and diethylenetriaminepentaacetic acid [DTPA]) showed that discrepancies in treatment protocols and open questions remain: How to proceed in case of repeated release of radioiodines? Which dosage for Prussian Blue? For which radionuclides is DTPA really effective? This paper brings elements to answer these questions.</p> </abstract>