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ChemInform Abstract: Acid‐Mediated Ring‐Expansion Reaction of N‐Aryl‐2‐vinylazetidines: Synthesis and Unanticipated Reactivity of Tetrahydrobenzazocines. Issue 44 (4th November 2014)
Record Type:
Journal Article
Title:
ChemInform Abstract: Acid‐Mediated Ring‐Expansion Reaction of N‐Aryl‐2‐vinylazetidines: Synthesis and Unanticipated Reactivity of Tetrahydrobenzazocines. Issue 44 (4th November 2014)
Main Title:
ChemInform Abstract: Acid‐Mediated Ring‐Expansion Reaction of N‐Aryl‐2‐vinylazetidines: Synthesis and Unanticipated Reactivity of Tetrahydrobenzazocines.
<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>In the presence of 1.5 equivalents of H<sub>2</sub>SO<sub>4</sub>, vinylazetidines are found to undergo ring expansion to benzazocine derivatives like (II) which are unstable undergoing ring contraction to vinyltetrahydroquinolines (III) under slightly acidic conditions.</p> </abstract>