Oral human papillomavirus type‐specific infection in HIV‐infected men: a prospective cohort study among men who have sex with men and heterosexual men. (21st January 2014)

• Record Type: Journal Article
• Authors: Darwich, L.; Cañadas, M. P.; Videla, S.; Coll, J.; Molina‐López, R. A.; Cobarsi, P.; Sirera, G.; Clotet, B.; the Can Ruti HIV‐HPV Team; Paul, M.
• Is Part Of: Clinical microbiology and infection. Volume 20:Number 9(2014:Sep.)
• Page Start: O585
• Page End: O589
• Publication Date: 2014-01-21
• Subjects: Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1111/1469-0691.12523
• Languages: English
• ISSNs: 1198-743X

Abstract

<abstract abstract-type="main" id="clm12523-abs-0001"> <title>Abstract</title> <p>The natural history of type‐specific oral infection of human papillomavirus (HPV) was assessed in a cohort of HIV‐infected men (538 men who have sex with men (MSM); 195 heterosexuals). Risk factors associated with oral HPV infections were examined. The overall prevalence of HPV was 16%: HPV‐16 was the most prevalent type (3.7% MSM; 7.8% heterosexuals). The prevalence of HPV‐16 in heterosexuals was associated with CD4 nadir counts &lt;200 cells/<italic>μ</italic>L (OR_adjusted = 3.0, 95% CI, 1.4–6.3). The overall incidence of HPV was similar between groups (11%), but the incidence of HPV‐16 was higher in heterosexuals (OR_adjusted = 3.2, 95% CI, 1.1–9.5). Not only MSM but also HIV‐infected heterosexual men are at risk of HPV infection. Regular and careful oral inspection is needed.</p> </abstract>