Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses. Issue 11 (19th August 2014)

• Record Type: Journal Article
• Authors: Gaye, Alioune; Faye, Oumar; Diagne, Cheikh T.; Faye, Ousmane; Diallo, Diawo; Weaver, Scott C.; Sall, Amadou A.; Diallo, Mawlouth
• Is Part Of: Tropical medicine & international health. Volume 19:Issue 11(2014:Nov.)
• Page Start: 1355
• Page End: 1359
• Publication Date: 2014-08-19
• Subjects: Tropical medicine -- Periodicals; Public health -- Periodicals; 616.988
• DOI: 10.1111/tmi.12373
• Languages: English
• ISSNs: 1360-2276

Abstract

<abstract abstract-type="main" id="tmi12373-abs-0001"> <title>Abstract</title> <sec id="tmi12373-sec-0001" sec-type="section"> <title>Objective</title> <p>To investigate the potential for domestic and wild populations of <italic>Aedes aegypti</italic> from Dakar and Kedougou to develop a disseminated infection after exposure to DENV‐3 and DENV‐1.</p> </sec> <sec id="tmi12373-sec-0002" sec-type="section"> <title>Methods</title> <p>We have exposed sylvatic and urban population of <italic>Ae. aegypti</italic> from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT–PCR to estimate the infection and dissemination rates.</p> </sec> <sec id="tmi12373-sec-0003" sec-type="section"> <title>Results</title> <p>The data indicated low susceptibility to DENV‐3 (infection: 2.4–15.2%, and dissemination rates: 0–8.3%) and higher susceptibility to DENV‐1 (infection and dissemination rates up to 50%).</p> </sec> <sec id="tmi12373-sec-0004" sec-type="section"> <title>Conclusion</title> <p> <italic>Aedes aegypti</italic> from Senegal seem able to develop a disseminated infection of DENV‐1 and DENV‐3. Further studies are needed to test their ability to transmit the two serotypes.</p> </sec> </abstract>