First case of disseminated cryptococcosis in a Gorilla gorilla. Issue 11 (25th June 2014)

• Record Type: Journal Article
• Authors: Mischnik, Alexander; Stockklausner, Julia; Hohneder, Nicole; Jensen, Henrik E.; Zimmermann, Stefan; Reuss, David E.; Rickerts, Volker; Tintelnot, Kathrin; Stockklausner, Clemens
• Is Part Of: Mycoses. Volume 57:Issue 11(2014)
• Page Start: 664
• Page End: 671
• Publication Date: 2014-06-25
• Subjects: Pathogenic fungi -- Periodicals; Medical mycology -- Periodicals; 616.969
• DOI: 10.1111/myc.12215
• Languages: English
• ISSNs: 0933-7407

Abstract

<abstract abstract-type="main" id="myc12215-abs-0001"> <title>Summary</title> <p>In humans, <italic>Cryptococcus</italic> mainly infects individuals with HIV infection or other types of immunosuppression. Here, we report the first case of disseminated cryptococcosis in a simian immunodeficiency virus‐negative 27‐year‐old female <italic>Gorilla gorilla</italic> presenting with lethargy, progressive weight loss and productive cough. The diagnosis was confirmed by positive lung biopsy culture, serum cryptococcal antigen, and cerebral histopathology demonstrating encapsulated yeasts. Molecular characterisation of lung culture isolate yielded <italic>Cryptococcus neoformans</italic> var. <italic>grubii</italic>. An immune‐deficiency could not be demonstrated.</p> </abstract>