Palladium(II) Chloride‐Catalyzed Aerobic Oxidative Intermolecular Cycloaddition Reaction of 2‐Alkynylbenz‐ aldehydes and Electron‐Deficient Terminal Alkenes: An Efficient Synthesis of Naphthyl Ketones. Issue 14 (3rd September 2014)

• Record Type: Journal Article
• Authors: Janreddy, Donala; Kavala, Veerababurao; Kotipalli, Trimurtulu; Kuo, Chun‐Wei; Kuo, Ting‐Shen; Chen, Mei‐Ling; He, Chiu‐Hui; Yao, Ching‐Fa
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 14/15(2014)
• Page Start: 3083
• Page End: 3091
• Publication Date: 2014-09-03
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201400180
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>We describe a simple and efficient synthetic methodology for the synthesis of a library of 2, 4‐dicarbonyl‐substituted naphthalene derivatives through the PdCl₂‐catalyzed aerobic oxidative intermolecular cycloaddition of 2‐alkynylbenzaldehydes to some electron‐deficient terminal alkenes. A wide variety of functionalized 2‐alkynylbenzaldehydes and electron‐deficient alkenes were examined for this reaction to deliver the corresponding naphthyldicarbonyl compounds in moderate to good yields.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh1fbrp3sg" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>