Impact of broader sharing on the transport time for deceased donor livers. Issue 10 (October 2014)
- Record Type:
- Journal Article
- Title:
- Impact of broader sharing on the transport time for deceased donor livers. Issue 10 (October 2014)
- Main Title:
- Impact of broader sharing on the transport time for deceased donor livers
- Authors:
- Gentry, Sommer E.
Chow, Eric K. H.
Wickliffe, Corey E.
Massie, Allan B.
Leighton, Tabitha
Segev, Dorry L. - Abstract:
- <abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Recent allocation policy changes have increased the sharing of deceased donor livers across local boundaries, and sharing even broader than this has been proposed as a remedy for persistent geographic disparities in liver transplantation. It is possible that broader sharing may increase cold ischemia times (CITs) and thus harm recipients. We constructed a detailed model of transport modes (car, helicopter, and fixed‐wing aircraft) and transport times between all hospitals, and we investigated the relationship between the transport time and the CIT for deceased donor liver transplants. The median estimated transport time was 2.0 hours for regionally shared livers and 1.0 hour for locally allocated livers. The model‐predicted transport mode was flying for 90% of regionally shared livers but for only 22% of locally allocated livers. The median CIT was 7.0 hours for regionally shared livers and 6.0 hours for locally allocated livers. Variation in the transport time accounted for only 14.7% of the variation in the CIT, and the transport time on average composed only 21% of the CIT. In conclusion, nontransport factors play a substantially larger role in the CIT than the transport time. Broader sharing will have only a marginal impact on the CIT but will significantly increase the fraction of transplants that are transported by flying rather than driving. <italic>Liver Transpl 20:1237‐1243,<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Recent allocation policy changes have increased the sharing of deceased donor livers across local boundaries, and sharing even broader than this has been proposed as a remedy for persistent geographic disparities in liver transplantation. It is possible that broader sharing may increase cold ischemia times (CITs) and thus harm recipients. We constructed a detailed model of transport modes (car, helicopter, and fixed‐wing aircraft) and transport times between all hospitals, and we investigated the relationship between the transport time and the CIT for deceased donor liver transplants. The median estimated transport time was 2.0 hours for regionally shared livers and 1.0 hour for locally allocated livers. The model‐predicted transport mode was flying for 90% of regionally shared livers but for only 22% of locally allocated livers. The median CIT was 7.0 hours for regionally shared livers and 6.0 hours for locally allocated livers. Variation in the transport time accounted for only 14.7% of the variation in the CIT, and the transport time on average composed only 21% of the CIT. In conclusion, nontransport factors play a substantially larger role in the CIT than the transport time. Broader sharing will have only a marginal impact on the CIT but will significantly increase the fraction of transplants that are transported by flying rather than driving. <italic>Liver Transpl 20:1237‐1243, 2014</italic>. © 2014 AASLD.</p> </abstract> … (more)
- Is Part Of:
- Liver transplantation. Volume 20:Issue 10(2014:Oct.)
- Journal:
- Liver transplantation
- Issue:
- Volume 20:Issue 10(2014:Oct.)
- Issue Display:
- Volume 20, Issue 10 (2014)
- Year:
- 2014
- Volume:
- 20
- Issue:
- 10
- Issue Sort Value:
- 2014-0020-0010-0000
- Page Start:
- 1237
- Page End:
- 1243
- Publication Date:
- 2014-10
- Subjects:
- Liver -- Transplantation -- Periodicals
Liver -- Diseases -- Periodicals
Liver Transplantation -- Periodicals
Foie -- Greffe -- Périodiques
617.5560592 - Journal URLs:
- https://journals.lww.com/lt/pages/currenttoc.aspx#232431391 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/lt.23942 ↗
- Languages:
- English
- ISSNs:
- 1527-6465
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 5280.522000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 3800.xml