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ChemInform Abstract: A General and Enantioselective Approach to Pentoses: A Rapid Synthesis of PSI‐6130, the Nucleoside Core of Sofosbuvir. Issue 42 (14th October 2014)
Record Type:
Journal Article
Title:
ChemInform Abstract: A General and Enantioselective Approach to Pentoses: A Rapid Synthesis of PSI‐6130, the Nucleoside Core of Sofosbuvir. Issue 42 (14th October 2014)
Main Title:
ChemInform Abstract: A General and Enantioselective Approach to Pentoses: A Rapid Synthesis of PSI‐6130, the Nucleoside Core of Sofosbuvir.
<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>TiCl<sub>2</sub>(OiPr)<sub>2</sub>‐promoted condensation of silylketene acetals (I) and the enantioenriched aldehyde (II) produces esters of type (III) in good diastereoselectivity.</p> </abstract>