Paclitaxel‐Coated Balloons in Refractory Nonanastomostic Airway Stenosis Following Lung Transplantation. Issue 10 (23rd July 2014)

• Record Type: Journal Article
• Authors: Greer, M.; Fuehner, T.; Warnecke, G.; Noack, H.; Heilmann, T.; Haverich, A.; Welte, T.; Gottlieb, J.
• Is Part Of: American journal of transplantation. Volume 14:Issue 10(2014:Oct.)
• Page Start: 2400
• Page End: 2405
• Publication Date: 2014-07-23
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ajt.12845
• Languages: English
• ISSNs: 1600-6135

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ajt12845-sec-0001" sec-type="section"> <p>Airway stenosis represents the commonest airway complication following lung transplantation, affecting between 7% and 18% of patients. Existing treatment options offer limited efficacy and can cause additional patient morbidity. Paclitaxel‐coated balloons (PCB) have proved effective in managing postinterventional coronary artery re‐stenosis. In a first‐in‐man study, we evaluated similar PCBs in refractory nonanastomotic airway stenosis in 12 patients. Following a single application, luminal patency was maintained in 50% at 270 days. No significant peri‐interventional or early postinterventional complications occurred. Given these encouraging initial findings, further studies appear warranted.</p> </sec> </abstract>