Intermolecular Conjugate Addition of Pyrroloindoline and Furoindoline Radicals to α, β‐Unsaturated Enones via Photoredox Catalysis. Issue 13 (10th September 2014)

• Record Type: Journal Article
• Authors: Zhou, Shupeng; Zhang, Deliang; Sun, Yu; Li, Ruofan; Zhang, Wenhao; Li, Ang
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 13(2014)
• Page Start: 2867
• Page End: 2872
• Publication Date: 2014-09-10
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201400702
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>We have developed an intermolecular conjugate addition of 3a‐pyrroloindoline/furoindoline radicals to α, β‐unsaturated enones, through visible‐light photoredox catalysis. Ir(ppy)₂(dtbbpy) PF₆ was found to be an effective promoter to initiate this reaction from readily available 3a‐bromopyrroloindolines/furoindolines. This method was exploited to prepare a series of indole terpenoid‐like compounds of potential biological interest.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh1c9js9g6" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>