Prenatal risk factors for depression: a critical review of the evidence and potential mechanisms. (20th June 2014)

• Record Type: Journal Article
• Authors: Braithwaite, E. C.; Murphy, S. E.; Ramchandani, P. G.
• Is Part Of: Journal of developmental origins of health and disease. Volume 5:Number 5(2014)
• Page Start: 339
• Page End: 350
• Publication Date: 2014-06-20
• Subjects: Developmental biology -- Periodicals; Embryology, Human -- Periodicals; Disease susceptibility -- Periodicals; Prenatal influences -- Periodicals; Diseases -- Causes and theories of causation -- Periodicals; 612.64
• DOI: 10.1017/S2040174414000324
• Languages: English
• ISSNs: 2040-1744

Abstract

<abstract abstract-type="normal"> <title> <x content-type="archive" xml:space="preserve">Abstract</x> </title> <p>Exposure to adverse experiences in early life increases the risk of depression during adulthood. Recent findings have highlighted that exposure of a fetus to an adverse intrauterine environment may also have implications for later offspring depression. This review considers the status of the evidence for these associations and the potential mechanisms underlying prenatal developmental risks for later depression, addressing the challenging possibility that environmental predisposition to depression may begin before birth.</p> </abstract>