Heterogeneous associations of insoluble dietary fibre intake with subsequent glycosylated Hb levels among Chinese adults with type 2 diabetes: a quantile regression approach. Issue 6 (28th September 2014)

• Record Type: Journal Article
• Authors: Tan, Ziwen; Ruan, Xiaonan; Chen, Yue; Jiang, Junyi; Zhou, Yi; Qiu, Hua; Qin, Guoyou; Xu, Wang Hong
• Is Part Of: British journal of nutrition. Volume 112:Issue 6(2014)
• Page Start: 958
• Page End: 963
• Publication Date: 2014-09-28
• Subjects: Nutrition -- Periodicals; 572.4
• DOI: 10.1017/S0007114514001615
• Languages: English
• ISSNs: 0007-1145

Abstract

<abstract abstract-type="normal"> <title> <x content-type="archive" xml:space="preserve">Abstract</x> </title> <p>Dietary fibre intake has been suggested to reduce blood glucose levels in diabetic patients, particularly when glycosylated Hb (HbA<sub>1c</sub>) levels are high. In the present study, we used a quantile regression (QR) approach to characterise the possible heterogeneous associations of dietary fibre intake with HbA<sub>1c</sub> levels in Chinese diabetic patients. A total of 497 diabetic patients participated in the baseline survey in 2006 and in the follow-up survey in 2011, both of which were conducted in Pudong New Area of Shanghai, China. Structured in-person interviews were conducted to collect information on demographic characteristics and lifestyle factors. Dietary intake was assessed using a validated FFQ. Blood samples were collected during the interviews for biochemical assays. QR models were used to examine the heterogeneous associations of dietary factors with HbA<sub>1c</sub> levels. A significant marginal association of insoluble dietary fibre intake with subsequent HbA<sub>1c</sub> levels was observed only when the HbA<sub>1c</sub> level was over 6·8 %. The associations appeared to be greater when the quantile levels of HbA<sub>1c</sub> were higher. The coefficient estimates were − 0·174 (95 % CI − 0·433, − 0·025) at the quantile of 0·60, − 0·200 (95 % CI − 0·306, − 0·008) at 0·70, − 0·221 (95 % CI − 0·426, − 0·117) at 0·80, and − 0·389 (95 % CI − 0·516, − 0·018) at 0·90. A similar pattern was observed for the associations of dietary glycaemic index (GI) value with HbA<sub>1c</sub> levels. In conclusion, the present results indicate that the associations of insoluble dietary fibre intake and GI value with subsequent HbA<sub>1c</sub> levels depend on glycaemic control status in Chinese diabetic patients. More studies are required to confirm our findings.</p> </abstract>